Research Associate, mRNA Engineering and Production
Biotechnology company developing epigenetic-reprogramming medicines for age-related disease, Bay Area
| Employer | Biotechnology company developing epigenetic-reprogramming medicines for age-related disease, Bay Area (not named) |
|---|---|
| Location | South San Francisco, CA (Bay Area) · On-site |
| Type & level | Full-time · Entry |
| Pay | USD 75 thousand–100 thousand base Source: pay range stated in the source posting |
| Visa path | O-1A fit (strong early-career candidates) |
| Role family | mRNA / Vaccine Platform Scientist |
About the role
The mRNA Engineering team makes the research-grade mRNA that supports the company's reprogramming and delivery research. This role runs the workflow from DNA template through in vitro transcription and purification, and hands the material to research and delivery scientists. It is designed for an early-career scientist who wants hands-on training in mRNA process development.
What you'll do
- Carry out established protocols for DNA template preparation, in vitro transcription and downstream purification to make research-grade mRNA
- Run routine analytical assays that check mRNA integrity and purity
- Help senior scientists troubleshoot production problems and run experiments to improve yield, purity and recovery
- Record every experiment in electronic lab notebooks and help write and update SOPs
- Track mRNA and raw material inventory, order reagents, and keep lab equipment in working order
- Coordinate material needs with delivery and research teams and present results at team meetings
Requirements
- B.S. in life sciences, chemistry, engineering or a related field with 1–2 years of full-time industry or academic research experience, or an M.S. in life sciences
- Hands-on molecular biology skills such as cloning, nucleic acid purification, PCR and gel electrophoresis
- Strong attention to detail and good documentation habits
- Ability to follow protocols accurately and juggle several tasks
- Clear communication and organizational skills
Nice to have
- Experience producing mRNA by IVT and downstream purification
- Familiarity with plasmid and mRNA analytics such as HPLC, UV-Vis and TapeStation or CGE
- Experience with plasmid DNA preparation and linearization
- Exposure to column-based purification and tangential flow filtration
- Experience with automated liquid handlers for mRNA purification
Pay & benefits
USD 75 thousand–100 thousand base. Health, dental and vision insurance, a 401(k) with company match, paid parental leave, 20 days of PTO plus holidays, and on-site meals and snacks.
Pay source: pay range stated in the source posting. Market data, not an offer from O1DMatch.
Visa path
People in mRNA process roles typically support an O-1A case with publications, patents, recognized research contributions, and recommendation letters from established scientists. This is an entry-level role, so it suits candidates who already have a notable research record. The posting states no citizenship restriction. An employer like this or a U.S. agent can file the petition, and approval depends on the individual's evidence.
How to get matched
- Take the free eligibility checkAn AI review of your background against the eight O-1 criteria, at check.o1dmatch.com.
- Create your profile with code WORKWITHUSIt unlocks the Starter plan at no cost. Tell us your field and the work you do today.
- Upload your evidenceEach document is sorted under the criterion it supports, and your criteria map shows what is still missing.
- Get matchedWe match strong profiles with U.S. employers hiring for roles like this one. Gigs you confirm with verified companies count toward your itinerary, and at a score of 75 we connect you with an immigration attorney.
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